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Patent Foramen Ovale, or PFO, is a hole in the atrial septum that separates the atria. This allows oxygen-poor blood to flow from the left atria into the right atria. This increases the volume of blood in the heart. As a result both atria, the right ventricle, and the pulmonary artery are enlarged.
Most PFO defects can be closed by interventional catheterization technique. PFO may also be closed using a simple suture of patch technique.
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